{"product_id":"proteintech-85907-4-rr","title":"Proteintech, 85907-4-RR, GRK6 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe GRK6 (85907-4-RR) by Proteintech is a Recombinant antibody targeting GRK6 in WB, ELISA applications with reactivity to human samples\n85907-4-RR targets GRK6 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MCF-7 cells, U2Os cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGRK6 (G Protein-Coupled Receptor Kinase 6) is a member of the G protein-coupled receptor kinase (GRK) family, which plays a crucial role in regulating the activity of G protein-coupled receptors (GPCRs). GRK6 specifically phosphorylates the activated forms of GPCRs, initiating their desensitization, internalization, and signaling events that lead to receptor deactivation. This process is essential for maintaining proper cellular responses to extracellular signals.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag1992 Product name: Recombinant human GRK6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 54-451 aa of BC017272 Sequence: HSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCFLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKL Predict reactive species\nFull Name: G protein-coupled receptor kinase 6\nCalculated Molecular Weight: 66 kDa\nObserved Molecular Weight: 65 kDa\nGenBank Accession Number: BC017272\nGene Symbol: GRK6\nGene ID (NCBI): 2870\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P43250\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888758739113,"sku":"85907-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-85907-4-rr","provider":"Iright","version":"1.0","type":"link"}