{"product_id":"proteintech-87164-1-rr","title":"Proteintech, 87164-1-RR, Phospho-EGFR (Tyr1172) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-EGFR (Tyr1172) (87164-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-EGFR (Tyr1172) in WB, IF\/ICC, ELISA applications with reactivity to human samples\n87164-1-RR targets Phospho-EGFR (Tyr1172) in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: EGF treated A431 cells, Serum-free treated and EGF treated A431 cells\nPositive IF\/ICC detected in: EGF treated A431 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nERBB1, also named as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Phospho-EGFR (Tyr1172) is a phosphorylated form of the epidermal growth factor receptor (EGFR), which is a transmembrane glycoprotein receptor that belongs to the ErbB family of receptor tyrosine kinases (RTKs). This phosphorylation event is significant as it activates downstream signaling cascades that regulate various cellular processes, including cell growth, proliferation, and survival. Some scientists call EGFR Tyr1172 as EGFR Tyr1148, the site where the signaling peptide is removed.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)\nCalculated Molecular Weight: 1210 aa, 134 kDa\nObserved Molecular Weight: 175 kDa\nGenBank Accession Number: BC094761\nGene Symbol: EGFR\nGene ID (NCBI): 1956\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P00533\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888800977065,"sku":"87164-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-87164-1-rr","provider":"Iright","version":"1.0","type":"link"}