{"product_id":"proteintech-87281-1-rr","title":"Proteintech, 87281-1-RR, PLAGL1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe PLAGL1 (87281-1-RR) by Proteintech is a Recombinant antibody targeting PLAGL1 in WB, ELISA applications with reactivity to human samples\n87281-1-RR targets PLAGL1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells, MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPLAGL1 (Pleomorphic adenoma gene-like 1) is a crucial zinc-finger transcription factor acting as a tumor suppressor, regulating cell cycle, growth (apoptosis), and embryonic development, particularly involved in pancreatic function and imprinted expression (paternal allele). While its family member PLAG1 is an oncogene in salivary tumors, PLAGL1 often suppresses tumors, though its dysregulation is linked to transient neonatal diabetes mellitus (TNDM) and certain cancers, highlighting its complex role in growth control and metabolic homeostasis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag23073 Product name: Recombinant human PLAGL1 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 201-463 aa of BC074814 Sequence: RHTKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHSLTLSPPEQAAQPMQPLPESLASLHPSVSPGSPPPPLPNHKYNTTSTSYSPLASLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNTFGNSTLALGPGESLPHRLSCLGQQQQEPPLAMGTVSLGQLPLPPIPHVFSAGTGSAILPHFHHAFR Predict reactive species\nFull Name: pleiomorphic adenoma gene-like 1\nCalculated Molecular Weight: 463 aa, 51 kDa\nObserved Molecular Weight: 51 kDa\nGenBank Accession Number: BC074814\nGene Symbol: PLAGL1\nGene ID (NCBI): 5325\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9UM63\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888806613161,"sku":"87281-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-87281-1-rr","provider":"Iright","version":"1.0","type":"link"}