{"product_id":"proteintech-87289-1-rr","title":"Proteintech, 87289-1-RR, Phospho-LAT (Tyr220) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-LAT (Tyr220) (87289-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-LAT (Tyr220) in WB, ELISA applications with reactivity to human samples\n87289-1-RR targets Phospho-LAT (Tyr220) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nLAT is a membrane-localized adaptor protein which is primarily concentrated in microdomains by palmitoylation. Phospho-LAT (Tyr220) is a phosphorylated form of the Linker for Activation of T cells (LAT), a protein that plays a pivotal role in T cell receptor (TCR) signaling. LAT is involved in the assembly of the signaling complex that leads to T cell activation. Upon TCR engagement, LAT becomes phosphorylated at multiple tyrosine residues, including Tyr220. (PMID: 38746248)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: linker for activation of T cells\nCalculated Molecular Weight: 262 aa, 28 kDa\nObserved Molecular Weight: 36 kDa, 38 kDa\nGenBank Accession Number: BC011563\nGene Symbol: LAT\nGene ID (NCBI): 27040\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O43561\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888802713769,"sku":"87289-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-87289-1-rr","provider":"Iright","version":"1.0","type":"link"}