{"product_id":"proteintech-87294-1-rr","title":"Proteintech, 87294-1-RR, Phospho-ITPR1 (Ser1764) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-ITPR1 (Ser1764) (87294-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-ITPR1 (Ser1764) in WB, ELISA applications with reactivity to human, mouse, rat samples\n87294-1-RR targets Phospho-ITPR1 (Ser1764) in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. Phospho-ITPR1 (Thr853) is a phosphorylated form of the inositol-trisphosphate receptor type 1 (ITPR1) protein at threonine residue 853. This phosphorylation site is involved in the regulation of calcium signaling pathways within cells. The specific function and role of Thr853 phosphorylation in ITPR1's activity are not detailed in the provided resources, but phosphorylation events on ITPR1 are known to influence its function, which affects calcium release from the endoplasmic reticulum. Calcium signaling is critical for various cellular processes, including muscle contraction, neurotransmitter release, and cellular division. This antibody is equivalent to Ser1756 in rat.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: inositol 1,4,5-triphosphate receptor, type 1\nCalculated Molecular Weight: 314 kDa\nObserved Molecular Weight: 320 kDa\nGenBank Accession Number: NM_001378452\nGene Symbol: ITPR1\nGene ID (NCBI): 3708\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q14643\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888802320553,"sku":"87294-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-87294-1-rr","provider":"Iright","version":"1.0","type":"link"}