{"product_id":"proteintech-87394-1-rr","title":"Proteintech, 87394-1-RR, Phospho-NPM1 (Thr199) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-NPM1 (Thr199) (87394-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-NPM1 (Thr199) in WB, ELISA applications with reactivity to human samples\n87394-1-RR targets Phospho-NPM1 (Thr199) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: paclitaxel treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNucleophosmin (NPM1,B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). Phospho-NPM1 (Thr199) is a phosphorylated form of nucleophosmin (NPM1) at threonine 199, a residue that plays a critical role in cell cycle regulation and cancer development. Indeed, phosphorylation by CDK2\/cyclin E on Thr199 residue during G1 phase is critical for the NPM1 dissociation from the centrosome to initiate its duplication and the pre-mRNA processing. (PMID: 26993766)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: nucleophosmin (nucleolar phosphoprotein B23, numatrin)\nCalculated Molecular Weight: 33 kDa\nObserved Molecular Weight: 40 kDa\nGenBank Accession Number: NM_002520\nGene Symbol: NPM1\nGene ID (NCBI): 4869\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P06748\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888803434665,"sku":"87394-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-87394-1-rr","provider":"Iright","version":"1.0","type":"link"}