{"product_id":"proteintech-87510-1-rr","title":"Proteintech, 87510-1-RR, IL-17F Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe IL-17F (87510-1-RR) by Proteintech is a Recombinant antibody targeting IL-17F in WB, ELISA applications with reactivity to human samples\n87510-1-RR targets IL-17F in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Transfected with Human IL-17F CHO cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines,  IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F. IL-17 family plays crucial roles in host defense against microbial organisms and in the development of inflammatory diseases.  IL-17A is a pro-inflammatory cytokine that also has the capacity to promote angiogenesis and osteoclastogenesis. IL-17F shares the highest homology with IL-17A and signals via a receptor composed by the IL-17RA and IL-17RC subunits. IL-17A and IL-17F can form IL-17A\/A or IL-17F\/F homodimers, IL-17A\/F heterodimers are also formed. IL-17A and IL-17F, produced by the Th17 CD4(+) T cell lineage, have been linked to a variety of inflammatory and autoimmune conditions. IL-17F levels are elevated in sera and lesional psoriatic skin compared to non-lesional tissue. IL-17F also has been implicated in the development of neutrophilic airway inflammation.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg2823 Product name: recombinant human IL17F protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 31-163 aa of NM_052872.3 Sequence: RKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ Predict reactive species\nFull Name: interleukin 17F\nCalculated Molecular Weight: 18 kDa\nObserved Molecular Weight: 18-20 kDa\nGenBank Accession Number: NM_052872.3\nGene Symbol: IL-17F\nGene ID (NCBI): 112744\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q96PD4\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888768307369,"sku":"87510-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-87510-1-rr","provider":"Iright","version":"1.0","type":"link"}