{"product_id":"proteintech-98149-1-rr","title":"Proteintech, 98149-1-RR, Anti-Human IL-12RB1\/CD212 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe IL-12RB1\/CD212 (98149-1-RR) by Proteintech is a Recombinant antibody targeting IL-12RB1\/CD212 in FC applications with reactivity to human samples\n98149-1-RR targets IL-12RB1\/CD212 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: anti-CD3\/CD28 treated human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nInterleukin-12 receptor subunit beta-1 (IL-12RB1), also named as CD212, is a 662 amino acid protein, which contains 5 fibronectin type-III domains and belongs to the type I cytokine receptor family. IL-12RB1 localizes in the membrane and functions as an interleukin receptor which binds IL-12 with low affinity and is involved in IL-12 transduction. Associated with IL-12RB2 it forms a functional, high affinity receptor for IL-12. It can also associate with IL23R to form the interleukin-23 receptor which functions in IL-23 signal transduction probably through activation of the Jak-Stat signaling cascade.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant Protein Predict reactive species\nFull Name: interleukin 12 receptor, beta 1\nCalculated Molecular Weight: 662 aa, 73 kDa\nGenBank Accession Number: BC029121\nGene Symbol: IL12RB1\nGene ID (NCBI): 3594\nRRID: AB_3672294\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P42701\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888698871977,"sku":"98149-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-98149-1-rr","provider":"Iright","version":"1.0","type":"link"}