{"product_id":"proteintech-98319-2-mr","title":"Proteintech, 98319-2-MR, Anti-Human CD3 Mouse Recombinant Antibody","description":"Size: 100ug\nThe CD3 (98319-2-MR) by Proteintech is a Recombinant antibody targeting CD3 in IHC, FC applications with reactivity to human, monkey, non-human primates samples\n98319-2-MR targets CD3 in IHC, FC applications and shows reactivity with human, monkey, non-human primates samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:500-1:2000\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, monkey, non-human primates\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: unknow Predict reactive species\nFull Name: CD3e molecule, epsilon (CD3-TCR complex)\nCalculated Molecular Weight: 207 aa, 23 kDa\nGenBank Accession Number: BC049847\nGene Symbol: CD3\nGene ID (NCBI): 916\nENSEMBL Gene ID: ENSG00000198851\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P07766\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888542077097,"sku":"98319-2-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-98319-2-mr","provider":"Iright","version":"1.0","type":"link"}