{"product_id":"proteintech-98390-1-rr","title":"Proteintech, 98390-1-RR, Anti-Human JAM2\/CD322 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe JAM2\/CD322 (98390-1-RR) by Proteintech is a Recombinant antibody targeting JAM2\/CD322 in FC applications with reactivity to human samples\n98390-1-RR targets JAM2\/CD322 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: Transfected HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nJunctional adhesion molecules (JAMs) are integral membrane proteins belonging to the immunoglobulin (Ig) superfamily. JAMs are expressed by leukocytes, platelets, endothelial, and epithelial cells and localized at the tight junction of polarized cells and on the cell surface of leukocytes. JAM-2, also known as CD322, VE-JAM or JAM-B, is specifically expressed in lymphatic endothelial cells and endothelial venules. JAM2 regulates cell-cell adhesion and signaling by interacting with other tight junction proteins such as PAR-3 and ZO-1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg2914 Product name: Recombinant Human JAM2 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 29-236 aa of NM_021219.3 Sequence: FSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLN Predict reactive species\nFull Name: junctional adhesion molecule 2\nCalculated Molecular Weight: 33 kDa\nGenBank Accession Number: NM_021219.3\nGene Symbol: JAM2\nGene ID (NCBI): 58494\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P57087-1\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888555217065,"sku":"98390-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-98390-1-rr","provider":"Iright","version":"1.0","type":"link"}