{"product_id":"proteintech-apc-fca65595","title":"Proteintech, APC-FcA65595, FcZero-rAb™ APC Anti-Human CD18 (TS1\/18) Rabbit Recombinant Antibody","description":"Size: 100tests\nThe CD18 (APC-FcA65595) by Proteintech is a Recombinant antibody targeting CD18 in FC applications with reactivity to human samples\nAPC-FcA65595 targets CD18 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a\/CD18 (LFA-1) is expressed by all leukocytes, while CD11b\/CD18 (Mac-1) and CD11c\/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Human Beta 2 Integrin Predict reactive species\nFull Name: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)\nCalculated Molecular Weight: 85 kDa\nGenBank Accession Number: BC005861\nGene Symbol: CD18\nGene ID (NCBI): 3689\nENSEMBL Gene ID: ENSG00000160255\nConjugate: APC Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 650 nm \/ 660 nm\nExcitation Laser: Red Laser (633 nm)\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P05107\nStorage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888615837865,"sku":"APC-FcA65595","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-apc-fca65595","provider":"Iright","version":"1.0","type":"link"}