{"product_id":"revvity-es-030-a","title":"Revvity, ES-030-A, AequoScreen Adrenergic α Cell Line","description":"\u003cp\u003eOverview\u003cbr\u003e\nRevvity's AequoScreen double transfected cell lines are provided in two vials of frozen cells, each containing ∽2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available each cell line.\u003cbr\u003e\nAequoScreen technology is a generic GPCR technology that can be used with Gs, Gi, and Gq-coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of resulting flash luminescence signal.\u003cbr\u003e\nFeatures:\u003c\/p\u003e\n\n\u003cp\u003eFully automatable and miniaturizable to 1536\u003cbr\u003e\nEnables reduction in reagents and consumable costs\u003cbr\u003e\nHigh signal to background ratio enabling detection of agonists, antagonists and allosteric modulators\u003cbr\u003e\nRobust assay (Z′, CV values, solvent resistance) \u003cbr\u003e\nReduces number of false positives from autofluorescent compounds in screening libraries\u003cbr\u003e\nOption to work with cells in suspension to increase throughput\u003cbr\u003e\nAmenable use with calcium coupled ion channels and tyrosine kinase receptors\u003c\/p\u003e\n\n\u003cp\u003eRevvity’s AequoScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Please use link above to accept Terms and Conditions or to request an agreement for commercial use. \u003cbr\u003e\nApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-AequoScreen\u003cbr\u003e\nG-Alpha Coupling Protein-Gα 16\u003cbr\u003e\nG-Alpha Natural Receptor-G i \/G o\u003cbr\u003e\nHost Cell Line-CHO-K1\u003cbr\u003e\nHost Species-Human\u003cbr\u003e\nProduct Group-Cell Line\u003cbr\u003e\nReceptor-Adrenergic\u003cbr\u003e\nSecond Messenger Release-Calcium flux\u003cbr\u003e\nShipping Conditions-Shipped in Dry Ice\u003cbr\u003e\nSpecial Ordering Information-Requires accepted Terms and Conditions. Additional agreement needed for commercial use.\u003cbr\u003e\nTarget Class-GPCR\u003cbr\u003e\nTherapeutic Area-Cardiovascular Diabetes Gastrointestinal Inflammation Metabolic\u003cbr\u003e\nUnit Size-5 million\u003cbr\u003e\nValidation-Binding Calcium Fluorescence Calcium Luminescence\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46774513893545,"sku":"ES-030-A","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/revvity-es-030-a","provider":"Iright","version":"1.0","type":"link"}