{"product_id":"revvity-nex312010uc","title":"Revvity, NEX312010UC, AB-MECA, [ I]-(4-Amino-3-[ I]iodobenzyl-5`-N-)-, 10µCi","description":"\u003cp\u003eOverview\u003cbr\u003e\n10 µCiQuantities of AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)- are available for your research.\u003cbr\u003e\nWe offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.\u003cbr\u003e\nRadiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.\u003cbr\u003e\nReferences for NEX312:\u003c\/p\u003e\n\n\u003cp\u003eHaeusler, D., Grassinger, L., Fuchshuber, F. et al. (2015), Hide and seek: a comparative autoradiographic in vitro investigation of the adenosine A3 receptor, Eur J Nucl Med Mol Imaging, 42: 928-939.\u003cbr\u003e\nOngini, E., Dionisotti, S., Gessi, S. et al. (1999), Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors, Naunyn-Schmiedeberg's Arch Pharmacol, 359: 7-10. Molecular Weight-523\u003cbr\u003e\nSpecific Activity-2200 Ci\/mmol  (81.4 TBq\/mmol)\u003cbr\u003e\nCAS Number-152918-26-8\u003c\/p\u003e\n\n\u003cp\u003eApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-NEN Radiochemicals\u003cbr\u003e\nBuffer\/Solvent-Methanol\u003cbr\u003e\nDetection Modality-Radiometric\u003cbr\u003e\nFresh Lot Days-Second Monday of each month\u003cbr\u003e\nLabel Position-Nominally Labeled\u003cbr\u003e\nMolecular Formula-C18H21N7O4\u003cbr\u003e\nPackaging-NENSure vial\u003cbr\u003e\nRadioisotope-125 I\u003cbr\u003e\nReceptor-Adenosine\u003cbr\u003e\nShipping Information-Shipped Ambient\u003cbr\u003e\nShipping Conditions-Shipped Ambient\u003cbr\u003e\nSpecial Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.\u003cbr\u003e\nStorage Conditions-4°C\u003cbr\u003e\nTherapeutic Area-Cardiovascular CNS \u0026amp; Neurologic Inflammation Metabolic Disorders\u003cbr\u003e\nUnit Size-10 µCi\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46774512222377,"sku":"NEX312010UC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/revvity-nex312010uc","provider":"Iright","version":"1.0","type":"link"}