{"product_id":"thermo-fisher-22309","title":"Thermo Fisher, 22309, GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)","description":"\u003cp\u003eGMBS (N-γ-maleimidobutyryl-oxysuccinimide ester) Thermo Scientific Pierce GMBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.\u003cbr\u003e\n3 angstroms).\u003cbr\u003e\nFeatures of GMBS:\u003cbr\u003e\n•Reactive groups:NHS esterandmaleimide\u003cbr\u003e\n•Reactive toward: amino and sulfhydryl groups\u003cbr\u003e\n• C4-homolog of aliphatic spacer series which includesAMAS,BMPS, GMBS andEMCS\u003cbr\u003e\n• NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds\u003cbr\u003e\n• Maleimides react with -SH groups at pH 6.\u003cbr\u003e\n5-7.\u003cbr\u003e\n5, forming stable thioether linkages\u003cbr\u003e\n• Non-cleavable\u003cbr\u003e\n• Water-insoluble (dissolve first in DMF or DMSO); compare toSulfo-GMBS\u003cbr\u003e\n• Short aliphatic spacer has low potential for eliciting an immune responseProduct References:Crosslinker Application Guide -- search for recent literature references for this productCell Permeability: Yes\u003cbr\u003e\nDescription: GMBS\u003cbr\u003e\nForm: Powder\u003cbr\u003e\nLabeling Method: Chemical Labeling\u003cbr\u003e\nMolecular Weight (g\/mol): 280.\u003cbr\u003e\n23\u003cbr\u003e\nPEGylated: No\u003cbr\u003e\nProduct Line: Pierce™\u003cbr\u003e\nQuantity: 50 mg\u003cbr\u003e\nReactive Moiety: Maleimide, NHS Ester\u003cbr\u003e\nShipping Condition: Ambient\u003cbr\u003e\nSolubility: DMF, DMSO\u003cbr\u003e\nSpacer Arm Length: 7.\u003cbr\u003e\n3 Å\u003cbr\u003e\nWater Soluble: No\u003cbr\u003e\nChemical Reactivity: Amine-Sulfhydryl\u003cbr\u003e\nCleavable: No\u003cbr\u003e\nCrosslinker Type: Heterobifunctional\u003cbr\u003e\nFormat: Standard\u003cbr\u003e\nProduct Type: Crosslinker\u003cbr\u003e\nSpacer: Short (\u0026lt;10 Å)\u003cbr\u003e\nUnit Size: Each\u003c\/p\u003e","brand":"Thermo Fisher","offers":[{"title":"Default Title","offer_id":45788944040105,"sku":"22309","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/thermo-fisher-22309","provider":"Iright","version":"1.0","type":"link"}