{"product_id":"abcam-ab104819","title":"Abcam, ab104819, Recombinant Human TSTD1 protein","description":"\u003cp\u003eSize: 50µg \/ 250µg\u003cbr\u003e\nRecombinant Human TSTD1 protein is a Human Full Length protein, in the 1 to 115 aa range, expressed in Escherichia coli, with \u0026gt;95%, suitable for SDS-PAGE, Mass Spec.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;95% SDS-PAGE,\u003cbr\u003e\nExpression system:Escherichia coli,\u003cbr\u003e\nTags:His tag N-Terminus,\u003cbr\u003e\nApplications:SDS-PAGE, Mass SpecSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q8NFU3,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nTSTD1 also known as thiosulfate sulfurtransferase-like domain-containing 1 is a protein that has a mechanical role as a sulfurtransferase enzyme. Weighing approximately 20 kDa TSTD1 catalyzes the transfer of sulfur and is involved in detoxification processes. This protein shows expression in various tissues with a notable presence in the liver and kidney where detoxification is highly active. Its role in these tissues suggests that TSTD1 may contribute to processes that maintain cellular homeostasis by managing sulfur-containing compounds.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nTSTD1 supports cellular processes by facilitating the conversion of thiosulfate to sulfite and hydrogen sulfide contributing to the metabolism of sulfur. Although not identified as part of a large protein complex TSTD1 interacts with other enzymes in networks managing sulfur metabolism. This interaction emphasizes its role in pathways ensuring the balance of sulfur species which are critical for detoxifying potentially harmful compounds.\u003cbr\u003e\nPathways\u003cbr\u003e\nTSTD1 holds relevance in sulfur metabolism and the hydrogen sulfide signaling pathway. It impacts the sulfur relay system by working alongside proteins like rhodanese and thioredoxin which both participate in similar sulfur transfer processes. By influencing the production and regulation of hydrogen sulfide TSTD1 may affect cellular signaling and defense mechanisms against oxidative stress.\u003cbr\u003e\nResearch links TSTD1 to conditions involving oxidative stress and mitochondrial dysfunction such as chronic kidney disease. In this context TSTD1's association with thioredoxin and its reduced sulfur metabolite activity suggest involvement in protecting against oxidative damage. Furthermore investigations into mitochondrial disorders highlight potential roles where TSTD1 mutations or dysregulation might contribute to disease progression indicating a possible target for therapeutic strategies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844022587561,"sku":"ab104819","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab104819","provider":"Iright","version":"1.0","type":"link"}