{"product_id":"abcam-ab11089","title":"Abcam, ab11089, Anti-CD3 antibody [CD3-12]","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nAnti-CD3 antibody [CD3-12] (ab11089) is a rat monoclonal antibody detecting CD3 in  Western Blot, Flow Cytometry (Intra), Flow Cytometry, IHC-P . Suitable for  Human, Mouse, Rat . - Over 100 publications - Trusted since 2004\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rat,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:CD3-12,\u003cbr\u003e\nIsotype:IgG1,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:Flow Cyt, WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human CD3E. The exact immunogen used to generate this antibody is proprietary information.P07766,\u003cbr\u003e\nSpecificity:IHC-P is not recommended in Human samples.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nProduct Specifications\u003cbr\u003e\nAnti-CD3 antibody [CD3-12] (ab11089) is a rat recombinant monoclonal antibody and is validated for use in in human, mouse, rat samples.\u003cbr\u003e\nAnti-CD3 antibody [CD3-12] (ab11089) specifically detects CD3 (UniProt ID: P07766; Molecular weight: 21kDa) and is sold in 100 µg and 1 mg selling sizes.\u003cbr\u003e\nQuality and Validation\u003cbr\u003e\nAbcam's high quality manufacturing and validation processes ensure Anti-CD3 antibody [CD3-12] (ab11089) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.\u003cbr\u003e\nAnti-CD3 antibody [CD3-12] (ab11089) has been cited over 104 times in peer reviewed journals and is trusted by the scientific community.\u003cbr\u003e\nAnti-CD3 antibody [CD3-12] (ab11089) has 18 independent reviews from customers.\u003cbr\u003e\nRelated Products\u003cbr\u003e\nConjugation-ready, carrier free format available for antibody clone CD3-12 -\u003cbr\u003e\nab255972\u003cbr\u003e\nAntibody clone CD3-12 is also available pre-conjugated to a variety of labels for your convenience - FITC (\u003cbr\u003e\nab34722\u003cbr\u003e\nTarget Information\u003cbr\u003e\nCD3, or Cluster of Differentiation 3, is a protein complex and T cell co-receptor that plays a crucial role in the activation of T cells, which are essential for the immune response. In oncology, CD3 is particularly significant due to its involvement in cancer immunotherapy. CD3 is targeted to enhance the body's ability to fight cancer. Bispecific antibodies (bsAbs) that target CD3 and a tumor antigen bring T cells into close proximity with cancer cells, promoting their destruction.\u003cbr\u003e\nThis product has switched from a hybridoma to recombinant production method on 1st November 2024.\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844214804649,"sku":"ab11089","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab11089","provider":"Iright","version":"1.0","type":"link"}