{"product_id":"abcam-ab113455","title":"Abcam, ab113455, Histone Demethylase (H3K4) Activity Quantification Assay Kit","description":"\u003cp\u003eSize: 48Test \/ 96Test\u003cbr\u003e\nHistone Demethylase (H3K4) Activity Quantification Assay Kit (ab113455) allows the user to measure activity\/inhibition of H3K4 specific histone demethylases using cell\/ tissue extracts.\u003cbr\u003e\nKey facts\u003cbr\u003e\nSample types:Tissue Extracts, Cell Lysate,\u003cbr\u003e\nAssay type:Enzyme activity,\u003cbr\u003e\nAssay time:3h,\u003cbr\u003e\nAssay Platform:Microplate reader\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nHistone Demethylase (H3K4) Activity Quantification Assay Kit (ab113455) allows the user to measure activity\/inhibition of H3K4 specific histone demethylases using cell\/ tissue extracts. The kit is ready-to-use and provides all the essential components needed for measuring histone demethylase H3K4 specific activity\/inhibition from a broad range of species including mammalian cells\/tissues, plants, and bacteria.\u003cbr\u003e\nMethylation of histone H3 at lysine 4 (H3K4) is thought to be a global epigenetic mark in euchromatin and a mediator of activated transcription. H3K4 demethylation is regulated by KDM1\/LSD1, which can remove di- and mono-methylation from H3K4, and the JARID proteins such as RBP2 which catalyzes the removal of methylation through a hydroxylation reaction.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions-Multi, Appropriate long-term storage conditions-Multi, Storage information-Please refer to protocols\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843650637993,"sku":"ab113455","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab113455","provider":"Iright","version":"1.0","type":"link"}