{"product_id":"abcam-ab120011","title":"Abcam, ab120011, AMN082 dihydrochloride, mGlu7 agonist","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 465.5 Da, Purity \u0026gt;98%. Potent, selective, orally active and brain penetrant mGlu7 receptor agonist. Potently inhibits cAMP accumulation and stimulates GTP binding (EC50 = 64-290 nM) in mGluR7 transfected cells. Selective over mGlu1, 2, 3, 4,5, 6, and 8, ionotropic receptors (up to 10 μM). Elevates plasma stress hormones *in vivo*. Induces mGlu7 receptor internalisation in dissociated hippocampal neurones.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:97075-46-2,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:465.5 Da,\u003cbr\u003e\nMolecular formula:C28H30Cl2N2,\u003cbr\u003e\nPubChem:11698390,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in water to 5 mMSoluble in ethanol to 1 mMSoluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:Amn082 dihydrochloride,\u003cbr\u003e\nBiological description:Potent, selective, orally active and brain penetrant mGlu7 receptor agonist. Potently inhibits cAMP accumulation and stimulates GTP binding (EC50 = 64-290 nM) in mGluR7 transfected cells. Selective over mGlu1, 2, 3, 4,5, 6, and 8, ionotropic receptors (up to 10 μM). Elevates plasma stress hormones *in vivo*. Induces mGlu7 receptor internalisation in dissociated hippocampal neurones.,\u003cbr\u003e\nCanonical smiles:C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C28H28N2.2ClH\/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)29-21-22-30-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26;;\/h1-20,27-30H,21-22H2;2*1H,\u003cbr\u003e\nInChiKey:YRQCDCNQANSUPB-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:N,N'-dibenzhydrylethane-1,2-diamine;dihydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847409946793,"sku":"ab120011","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab120011","provider":"Iright","version":"1.0","type":"link"}