{"product_id":"abcam-ab120245","title":"Abcam, ab120245, MMPIP, mGlu7 allosteric antagonist","description":"\u003cp\u003eSize: 1mg \/ 10mg \/ 50mg\u003cbr\u003e\nMW 333.3 Da, Purity \u0026gt;98%. Potent, selective allosteric antagonist at mGlu7 receptors. Inhibits agonist-induced intracellular calcium mobilisation and cAMP accumulation (IC50 values are 26 and 610 nM). Also displays intrinsic activity; increasing forskolin-induced cAMP accumulation in the absence of an agonist. Exhibits no significant activity at mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, and mGluR8. Also available in Kit: mGlu antagonists (ab120322).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:479077-02-6,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:333.3 Da,\u003cbr\u003e\nMolecular formula:C19H15N3O3,\u003cbr\u003e\nPubChem:9945530,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 10 mM,\u003cbr\u003e\nBiochemical name:Mmpip,\u003cbr\u003e\nBiological description:Potent, selective allosteric antagonist at mGlu7 receptors. Inhibits agonist-induced intracellular calcium mobilisation and cAMP accumulation (IC50 values are 26 and 610 nM). Also displays intrinsic activity; increasing forskolin-induced cAMP accumulation in the absence of an agonist. Exhibits no significant activity at mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, and mGluR8. Also available in Kit: mGlu antagonists (ab120322),\u003cbr\u003e\nCanonical smiles:CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=NC=C3)C4=CC=C(C=C4)OC,\u003cbr\u003e\nInChi:InChI=1S\/C19H15N3O3\/c1-22-15(12-3-5-14(24-2)6-4-12)11-16-17(19(22)23)18(21-25-16)13-7-9-20-10-8-13\/h3-11H,1-2H3,\u003cbr\u003e\nInChiKey:PDWYBOZNEVALOV-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-yl-[1,2]oxazolo[4,5-c]pyridin-4-one\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847427870889,"sku":"ab120245","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab120245","provider":"Iright","version":"1.0","type":"link"}