{"product_id":"abcam-ab120644","title":"Abcam, ab120644, Withaferin A from Withania somnifera","description":"\u003cp\u003eSize: 1mg \/ 5mg\u003cbr\u003e\nMW 470.6 g\/mol, Purity \u0026gt;98%. Naturally occurring withanolide\/steroidal lactone with anticancer properties. Demonstrates a number of cellular effects including the covalent binding to annexin II, inhibition of chymotrypsin-like activity, PKC and caspase 3. Causes translocation of cyctochrome C to the nucleous and the cleavage of PLC-γ1. Down-regulates Notch 1, 3, cdc25C, phosphorylated Akt and bcl-2 proteins.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:5119-48-2,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nSource:Withania somnifera,\u003cbr\u003e\nMolecular weight:470.6 g\/mol,\u003cbr\u003e\nMolecular formula:C28H38O6,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in ethanol,\u003cbr\u003e\nBiological description:Naturally occurring withanolide\/steroidal lactone with anticancer properties. Demonstrates a number of cellular effects including the covalent binding to annexin II, inhibition of chymotrypsin-like activity, PKC and caspase 3. Causes translocation of cyctochrome C to the nucleous and the cleavage of PLC-γ1. Down-regulates Notch 1, 3, cdc25C, phosphorylated Akt and bcl-2 proteins.,\u003cbr\u003e\nIUPAC Name:(4Î²,5Î²,6Î²,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid Î´-lactone\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847428690089,"sku":"ab120644","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab120644","provider":"Iright","version":"1.0","type":"link"}