{"product_id":"abcam-ab125000","title":"Abcam, ab125000, Anti-ATTY antibody [EPR6121]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal ATTY antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR6121,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nATTY is a protein with a recognized role in cellular processes. It is also known as gene product X and carries a molecular mass of approximately 58 kDa. This protein shows high expression in tissues such as the brain and heart suggesting its involvement in key processes within these areas. ATTY is primarily located in the cytoplasm where it engages in interactions essential for its mechanical function.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nATTY contributes significantly to intracellular signaling. It acts as a scaffold for assembling protein complexes which enables efficient signal transduction. Within the cell ATTY interacts with other proteins to help modulate signal pathways integral to cellular communication and response. This role highlights the importance of ATTY in maintaining cellular homeostasis and function.\u003cbr\u003e\nPathways\u003cbr\u003e\nInvolvement extends to two significant biological pathways: the MAP kinase signaling pathway and the PI3K-Akt pathway. ATTY influences various signaling cascades that play roles in cell growth survival and proliferation. In these pathways it interacts with proteins such as ERK and Akt linking it to mechanisms that control cell fate and metabolism.\u003cbr\u003e\nATTY's function relates closely to conditions like neurodegenerative diseases and cardiovascular disorders. In Alzheimer's disease alterations in ATTY expression are observed and these changes may correlate with disease progression. Additionally in cardiovascular disorders ATTY's interactions with cardiac-specific proteins such as troponin may affect heart muscle function. Identifying these relationships allows for a better understanding of ATTY's role in pathology and potential therapeutic targeting.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850374172841,"sku":"ab125000","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab125000","provider":"Iright","version":"1.0","type":"link"}