{"product_id":"abcam-ab141048","title":"Abcam, ab141048, Fludarabine (FAMP), DNA synthesis inhibitor","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 285.23 Da, Purity \u0026gt;98%. DNA synthesis inhibitor. Prodrug converted to active metabolite F-ara-A which inhibits ribonucleotide reductase and competitively inhibits DNA polymerase. Also prevents DNA ligase I from joining DNA. Induces apoptosis. Active  in vivo .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:146-78-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:285.23 Da,\u003cbr\u003e\nMolecular formula:C10H12FN5O4,\u003cbr\u003e\nPubChem:8975,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:2-Fluoroadenosine,\u003cbr\u003e\nBiological description:DNA synthesis inhibitor. Prodrug converted to active metabolite F-ara-A which inhibits ribonucleotide reductase and competitively inhibits DNA polymerase. Also prevents DNA ligase I from joining DNA. Induces apoptosis. Active in vivo.,\u003cbr\u003e\nCanonical smiles:C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N,\u003cbr\u003e\nIsomeric smiles:C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)F)N,\u003cbr\u003e\nInChi:InChI=1S\/C10H12FN5O4\/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9\/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)\/t3-,5-,6-,9-\/m1\/s1,\u003cbr\u003e\nInChiKey:HBUBKKRHXORPQB-UUOKFMHZSA-N,\u003cbr\u003e\nIUPAC Name:(2R,3R,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847458607273,"sku":"ab141048","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab141048","provider":"Iright","version":"1.0","type":"link"}