{"product_id":"abcam-ab141527","title":"Abcam, ab141527, Fumagillin, methionine aminopeptidase-2 (MetAP2) inhibitor","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 458.5 Da, Purity \u0026gt;95%. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2) (IC50 = 9.2 nM). Anti-angiogenic. Inhibits endothelial cell proliferation. Inhibits neovascularization and reduces diet-induced obesity*in vivo*. Orally active.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:23110-15-8,\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:458.5 Da,\u003cbr\u003e\nMolecular formula:C26H34O7,\u003cbr\u003e\nPubChem:3430,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 50 mM,\u003cbr\u003e\nBiochemical name:10-[[5-Methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid,\u003cbr\u003e\nBiological description:Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2) (IC50 = 9.2 nM). Anti-angiogenic. Inhibits endothelial cell proliferation. Inhibits neovascularization and reduces diet-induced obesity*in vivo*. Orally active.,\u003cbr\u003e\nCanonical smiles:CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C,\u003cbr\u003e\nInChi:InChI=1S\/C26H34O7\/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28\/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28),\u003cbr\u003e\nInChiKey:NGGMYCMLYOUNGM-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:10-[[5-methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847450349737,"sku":"ab141527","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab141527","provider":"Iright","version":"1.0","type":"link"}