{"product_id":"abcam-ab144228","title":"Abcam, ab144228, Concanamycin B, H+-ATPase inhibitor","description":"\u003cp\u003eSize: 25µg \/ 100µg \/ 500µg\u003cbr\u003e\nMW 852.1 Da, Purity \u0026gt;98%. Potent, selective vacuolar type H+-ATPase inhibitor. Antibiotic agent. Induces EGF-dependent apoptosis. Shows similar effects as Concanamycin A (ab144227) and Concanamycin C (ab144229). Shows potent antiviral effects (IC50 = 6 nM, HSV-1 replication).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:81552-33-2,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nSource:Streptomyces sp.,\u003cbr\u003e\nMolecular weight:852.1 Da,\u003cbr\u003e\nMolecular formula:C45H73NO14,\u003cbr\u003e\nPubChem:6440685,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in DMSO,\u003cbr\u003e\nBiochemical name:[(2R,3S,4R,6R)-6-[(2R,4R,5S,6R)-2-[(2S,3R,4S)-4-[(2R,3S,4E,6E,9R,10S,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-4-yl]oxy-4-hydroxy-2-methyloxan-3-yl] carbamate,\u003cbr\u003e\nBiological description:Potent, selective vacuolar type H+-ATPase inhibitor. Antibiotic agent. Induces EGF-dependent apoptosis. Shows similar effects as Concanamycin A (ab144227) and Concanamycin C (ab144229). Shows potent antiviral effects (IC50 = 6 nM, HSV-1 replication).,\u003cbr\u003e\nCanonical smiles:CC=CC1C(C(CC(O1)(C(C)C(C(C)C2C(C=CC=C(CC(C(C(C(C(C=C(C=C(C(=O)O2)OC)C)C)O)C)O)C)C)OC)O)O)OC3CC(C(C(O3)C)OC(=O)N)O)C,\u003cbr\u003e\nIsomeric smiles:C\/C=C\/[C@@H]1[C@H]([C@@H](C[C@@](O1)([C@@H](C)[C@@H]([C@H](C)[C@@H]2[C@H](\/C=C\/C=C(\/C[C@H]([C@@H]([C@@H]([C@@H]([C@@H](\/C=C(\/C=C(\/C(=O)O2)\\OC)\\C)C)O)C)O)C)\\C)OC)O)O)O[C@H]3C[C@H]([C@@H]([C@H](O3)C)OC(=O)N)O)C,\u003cbr\u003e\nInChi:InChI=1S\/C45H73NO14\/c1-13-15-33-27(6)36(57-37-21-32(47)42(31(10)56-37)59-44(46)52)22-45(53,60-33)30(9)40(50)29(8)41-34(54-11)17-14-16-23(2)18-25(4)38(48)28(7)39(49)26(5)19-24(3)20-35(55-12)43(51)58-41\/h13-17,19-20,25-34,36-42,47-50,53H,18,21-22H2,1-12H3,(H2,46,52)\/b15-13+,17-14+,23-16+,24-19+,35-20-\/t25-,26-,27-,28+,29+,30+,31-,32-,33-,34+,36-,37+,38+,39-,40-,41-,42-,45-\/m1\/s1,\u003cbr\u003e\nInChiKey:AQXXGIBOZQZSAT-XDUMZDCNSA-N,\u003cbr\u003e\nIUPAC Name:[(2R,3S,4R,6R)-6-[(2R,4R,5S,6R)-2-[(2S,3R,4S)-4-[(2R,3S,4E,6E,9R,10S,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-4-yl]oxy-4-hydroxy-2-methyloxan-3-yl] carbamate\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847447859369,"sku":"ab144228","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab144228","provider":"Iright","version":"1.0","type":"link"}