{"product_id":"abcam-ab144268","title":"Abcam, ab144268, Heliquinomycin, Antibiotic agent","description":"\u003cp\u003eSize: 250µg \/ 500µg\u003cbr\u003e\nMW 698.6 Da, Purity \u0026gt;80%. Antibiotic agent. DNA helicase inhibitor (IC 50  values are 4.3 and 2.5 μM for DNA helicase B and MCM4\/6\/7 helicase respectively). Inhibits DNA replication (IC 50  values are 1 - 4 μM). Weak topoisomerase I and II inhibitor. Inhibits DNA and RNA synthesis. Does not inhibit protein synthesis. Induces G2\/M cell cycle arrest. Shows antibacterial effects. Inhibits cancer cell line growth (IC 50  values are 1.4 - 4 μM).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:178182-49-5,\u003cbr\u003e\nPurity:\u0026gt;80%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nSource:Streptomyces sp.,\u003cbr\u003e\nMolecular weight:698.6 Da,\u003cbr\u003e\nMolecular formula:C33H30O17,\u003cbr\u003e\nPubChem:5470493,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in ethanolSoluble in DMSO,\u003cbr\u003e\nBiochemical name:Heliquinomycin,\u003cbr\u003e\nBiological description:Antibiotic agent. DNA helicase inhibitor (IC50 values are 4.3 and 2.5 μM for DNA helicase B and MCM4\/6\/7 helicase respectively). Inhibits DNA replication (IC50 values are 1 - 4 μM). Weak topoisomerase I and II inhibitor. Inhibits DNA and RNA synthesis. Does not inhibit protein synthesis. Induces G2\/M cell cycle arrest. Shows antibacterial effects. Inhibits cancer cell line growth (IC50 values are 1.4 - 4 μM).,\u003cbr\u003e\nCanonical smiles:CC1C(C(CC(O1)OC2C3=C(C4=C(C(=C3OC25C(CC6=C(O5)C(=C7C(=C6)C=C(OC7=O)C(=O)OC)O)O)O)C(=O)C(=CC4=O)OC)O)OC)O,\u003cbr\u003e\nIsomeric smiles:CC1C(C(CC(O1)O[C@@H]2C3=C(C4=C(C(=C3O[C@]25[C@@H](CC6=C(O5)C(=C7C(=C6)C=C(OC7=O)C(=O)OC)O)O)O)C(=O)C(=CC4=O)OC)O)OC)O,\u003cbr\u003e\nInChi:InChI=1S\/C33H30O17\/c1-10-23(36)15(44-3)9-18(46-10)48-30-22-25(38)20-13(34)8-14(43-2)24(37)21(20)27(40)29(22)50-33(30)17(35)7-12-5-11-6-16(31(41)45-4)47-32(42)19(11)26(39)28(12)49-33\/h5-6,8,10,15,17-18,23,30,35-36,38-40H,7,9H2,1-4H3\/t10?,15?,17-,18?,23?,30-,33-\/m1\/s1,\u003cbr\u003e\nInChiKey:MLFZQFHGXSVTGX-VJANPNJTSA-N,\u003cbr\u003e\nIUPAC Name:methyl (2R,3R,3'R)-3,4',9',10-tetrahydroxy-3'-(5-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847466274985,"sku":"ab144268","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab144268","provider":"Iright","version":"1.0","type":"link"}