{"product_id":"abcam-ab144501","title":"Abcam, ab144501, Pyrimidyn-7™, dynamin inhibitor","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 363.59 g\/mol, Purity \u0026gt;97%. Novel, potent dual action dynamin inhibitor (IC 50  values are 1.1 and 1.8 µM at dynamin I and II respectively). Only inhibitor to target two distinct domains of dynamin. Competitively inhibits both GTP and phospholipid binding. Reversibly inhibits clathrin mediated endocytosis (CME) and synaptic vesicle endocytosis (SVE) in nerve terminals.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1440126-94-2,\u003cbr\u003e\nPurity:\u0026gt;97%,\u003cbr\u003e\nForm:LiquidSee storage information,\u003cbr\u003e\nMolecular weight:363.59 g\/mol,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nBiological description:Novel, potent dual action dynamin inhibitor (IC50 values are 1.1 and 1.8 µM at dynamin I and II respectively). Only inhibitor to target two distinct domains of dynamin.Competitively inhibits both GTP and phospholipid binding. Reversibly inhibits clathrin mediated endocytosis (CME) and synaptic vesicle endocytosis (SVE) in nerve terminals.,\u003cbr\u003e\nCanonical smiles:CN(C)CCNC1NC(C)CC(NCCCCCCCCCCCC)N1,\u003cbr\u003e\nInChi:InChI=1S\/C21H41N5\/c1-5-6-7-8-9-10-11-12-13-14-15-22-20-18-19(2)24-21(25-20)23-16-17-26(3)4\/h18H,5-17H2,1-4H3,(H2,22,23,24,25),\u003cbr\u003e\nInChiKey:CKRZZHPNUCLRBE-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:N2-[2-(Dimethylamino)ethyl]-N4-dodecyl-6-methyl-2,4-pyrimidinediamine\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nSold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pyrimidyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847427182761,"sku":"ab144501","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab144501","provider":"Iright","version":"1.0","type":"link"}