{"product_id":"abcam-ab144572","title":"Abcam, ab144572, BIX 02188, MEK5 inhibitor","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 412.5 Da, Purity \u0026gt;98%. Potent, selective MEK5 inhibitor (IC 50  = 4.3 nM). Blocks phosphorlyation of ERK5, without affecting phosphorylation of ERK1\/2. Induces apoptosis in FLT3-ITD cells. Centrally active  in vivo. .\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:412.5 Da,\u003cbr\u003e\nMolecular formula:C25H24N4O2,\u003cbr\u003e\nPubChem:66524294,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:CID 66524294,\u003cbr\u003e\nBiological description:Potent, selective MEK5 inhibitor (IC50 = 4.3 nM). Blocks phosphorlyation of ERK5, without affecting phosphorylation of ERK1\/2. Induces apoptosis in FLT3-ITD cells. Centrally active in vivo.,\u003cbr\u003e\nCanonical smiles:CN(C)CC1=CC(=CC=C1)NC(=C2C3=C(C=C(C=C3)C(=O)N)NC2=O)C4=CC=CC=C4,\u003cbr\u003e\nIsomeric smiles:CN(C)CC1=CC(=CC=C1)N\/C(=C\\2\/C3=C(C=C(C=C3)C(=O)N)NC2=O)\/C4=CC=CC=C4,\u003cbr\u003e\nInChi:InChI=1S\/C25H24N4O2\/c1-29(2)15-16-7-6-10-19(13-16)27-23(17-8-4-3-5-9-17)22-20-12-11-18(24(26)30)14-21(20)28-25(22)31\/h3-14,27H,15H2,1-2H3,(H2,26,30)(H,28,31)\/b23-22-,\u003cbr\u003e\nInChiKey:FSZPIAXLCCQFCM-FCQUAONHSA-N,\u003cbr\u003e\nIUPAC Name:(3Z)-3-[[3-[(dimethylamino)methyl]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxamide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847455002793,"sku":"ab144572","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab144572","provider":"Iright","version":"1.0","type":"link"}