{"product_id":"abcam-ab144637","title":"Abcam, ab144637, CRT0066101, protein kinase D inhibitor","description":"\u003cp\u003eSize: 10mg\u003cbr\u003e\nMW 411.3 Da, Purity \u0026gt;99%. Potent and selective protein kinase D inhibitor (IC 50  values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active  in vivo  and  in vitro . Also available in simple stock solutions (ab146740) - add 1 ml of water to get an exact, ready-to-use concentration.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1883545-60-5,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:411.3 Da,\u003cbr\u003e\nMolecular formula:C18H24Cl2N6O,\u003cbr\u003e\nPubChem:136664697,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in water to 100 mM,\u003cbr\u003e\nBiochemical name:(R)-2-(4-((2-aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride,\u003cbr\u003e\nBiological description:Potent and selective protein kinase D inhibitor (IC50 values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active in vivo and in vitro.Also available in simple stock solutions (ab146740) - add 1 ml of water to get an exact, ready-to-use concentration.,\u003cbr\u003e\nCanonical smiles:CCC(CNC1=NC(=NC=C1)C2=C(C=CC(=C2)C3=CN(N=C3)C)O)N.Cl.Cl,\u003cbr\u003e\nIsomeric smiles:CC[C@H](CNC1=NC(=NC=C1)C2=C(C=CC(=C2)C3=CN(N=C3)C)O)N.Cl.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C18H22N6O.2ClH\/c1-3-14(19)10-21-17-6-7-20-18(23-17)15-8-12(4-5-16(15)25)13-9-22-24(2)11-13;;\/h4-9,11,14,25H,3,10,19H2,1-2H3,(H,20,21,23);2*1H\/t14-;;\/m1..\/s1,\u003cbr\u003e\nInChiKey:CXYCRYGNFKDPRH-FMOMHUKBSA-N,\u003cbr\u003e\nIUPAC Name:2-[4-[[(2R)-2-aminobutyl]amino]pyrimidin-2-yl]-4-(1-methylpyrazol-4-yl)phenol;dihydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nSold under license from CRT.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847428427945,"sku":"ab144637","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab144637","provider":"Iright","version":"1.0","type":"link"}