{"product_id":"abcam-ab145194","title":"Abcam, ab145194, AS601245, JNK inhibitor","description":"\u003cp\u003eSize: 1mg \/ 5mg \/ 25mg\u003cbr\u003e\nMW 372.4 Da, Purity \u0026gt;95%. Potent, selective, ATP competitive JNK inhibitor (IC 50  values are 150, 220 and 70 nM for hJNK1,2 and 3 respectively). Reduces cell adhesion and migration in cancer cells. Shows neuroprotective, anti-ischemic effects  in vivo . Blood-brain barrier and cell-permeable.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:372.4 Da,\u003cbr\u003e\nMolecular formula:C20H16N6S,\u003cbr\u003e\nPubChem:11422035,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 25 mM,\u003cbr\u003e\nBiochemical name:JNK Inhibitor V,\u003cbr\u003e\nBiological description:Potent, selective, ATP competitive JNK inhibitor (IC50 values are 150, 220 and 70 nM for hJNK1,2 and 3 respectively). Reduces cell adhesion and migration in cancer cells. Shows neuroprotective, anti-ischemic effects in vivo. Blood-brain barrier and cell-permeable.,\u003cbr\u003e\nCanonical smiles:C1=CC=C2C(=C1)NC(=C(C#N)C3=NC(=NC=C3)NCCC4=CN=CC=C4)S2,\u003cbr\u003e\nIsomeric smiles:C1=CC=C2C(=C1)N\/C(=C(\/C#N)\\C3=NC(=NC=C3)NCCC4=CN=CC=C4)\/S2,\u003cbr\u003e\nInChi:InChI=1S\/C20H16N6S\/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14\/h1-6,8-9,11,13,25H,7,10H2,(H,23,24,26)\/b19-15+,\u003cbr\u003e\nInChiKey:AVLYNJZZQYEFEA-XDJHFCHBSA-N,\u003cbr\u003e\nIUPAC Name:(2Z)-2-(3H-1,3-benzothiazol-2-ylidene)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847430885545,"sku":"ab145194","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab145194","provider":"Iright","version":"1.0","type":"link"}