{"product_id":"abcam-ab145638","title":"Abcam, ab145638, KN-93, CaM kinase II inhibitor","description":"\u003cp\u003eSize: 250µg\u003cbr\u003e\nMW 501 Da, Purity \u0026gt;98%. Potent, cell-permeable CaM kinase II inhibitor (IC 50  = 370 nM). Potent voltage gated K +  channel blocker (IC 50  = 307 nM, K V 1.5). Analog of water soluble KN-93 (ab120980). Suppresses early afterdepolarization. Induces ROS generation and apoptosis. Shows central effects  in vivo.  .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:139298-40-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:501 Da,\u003cbr\u003e\nMolecular formula:C26H29ClN2O4S,\u003cbr\u003e\nPubChem:5312122,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM (with warming),\u003cbr\u003e\nBiochemical name:Methoxybenzene-sulfonamide,\u003cbr\u003e\nBiological description:Potent, cell-permeable CaM kinase II inhibitor (IC50 = 370 nM). Potent voltage gated K+ channel blocker (IC50 = 307 nM, KV1.5). Analog of water soluble KN-93 (ab120980). Suppresses early afterdepolarization. Induces ROS generation and apoptosis. Shows central effects in vivo.,\u003cbr\u003e\nCanonical smiles:CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC,\u003cbr\u003e\nIsomeric smiles:CN(C\/C=C\/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC,\u003cbr\u003e\nInChi:InChI=1S\/C26H29ClN2O4S\/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25\/h3-16,30H,17-20H2,1-2H3\/b6-5+,\u003cbr\u003e\nInChiKey:LLLQTDSSHZREGW-AATRIKPKSA-N,\u003cbr\u003e\nIUPAC Name:N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called 2524 KN-93. 2524-250 is the same size as the 250 μg size of ab145638.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847490556073,"sku":"ab145638","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab145638","provider":"Iright","version":"1.0","type":"link"}