{"product_id":"abcam-ab145974","title":"Abcam, ab145974, PRIMA-1MET, p53 activity","description":"\u003cp\u003eSize: 10mg \/ 25mg\u003cbr\u003e\nMW 199.25 Da, Purity \u0026gt;98%. Methylated derivative of PRIMA-1 (ab141641). Restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation. Inhibits thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:5291-32-7,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:199.25 Da,\u003cbr\u003e\nMolecular formula:C10H17NO3,\u003cbr\u003e\nPubChem:52918385,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in water to 100 mMSoluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:Apr-246,\u003cbr\u003e\nBiological description:Methylated derivative of PRIMA-1 (ab141641). Restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation. Inhibits thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.,\u003cbr\u003e\nCanonical smiles:COCC1(C(=O)C2CCN1CC2)CO,\u003cbr\u003e\nInChi:InChI=1S\/C10H17NO3\/c1-14-7-10(6-12)9(13)8-2-4-11(10)5-3-8\/h8,12H,2-7H2,1H3,\u003cbr\u003e\nInChiKey:BGBNULCRKBVAKL-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847464800425,"sku":"ab145974","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab145974","provider":"Iright","version":"1.0","type":"link"}