{"product_id":"abcam-ab146597","title":"Abcam, ab146597, Dorsomorphin (Compound C) (DMSO solution), AMP-kinase inhibitor","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 399.5 Da, Purity \u0026gt;99%. Potent, selective and reversible inhibitor of AMP-kinase (K i  = 109 nM). Inhibits AMPK activation induced by AICAR (ab120358) and metformin (ab120847). Selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Does not affect ZAPK, SYK, PKCθ, PKA and JAK3. Cell-permeable. Also available in a water soluble form (Dorsomorphin dihydrochloride - ab144821).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:866405-64-3,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:LiquidSee storage information,\u003cbr\u003e\nMolecular weight:399.5 Da,\u003cbr\u003e\nMolecular formula:C24H25N5O,\u003cbr\u003e\nPubChem:11524144,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nBiochemical name:Dorsomorphin,\u003cbr\u003e\nBiological description:Potent, selective and reversible inhibitor of AMP-kinase (Ki = 109 nM). Inhibits AMPK activation induced by AICAR (ab120358) and metformin (ab120847). Selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Does not affect ZAPK, SYK, PKCθ, PKA and JAK3. Cell-permeable.Also available in a water soluble form (Dorsomorphin dihydrochloride - ab144821),\u003cbr\u003e\nCanonical smiles:C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3,\u003cbr\u003e\nInChi:InChI=1S\/C24H25N5O\/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20\/h4-11,16-18H,1-3,12-15H2,\u003cbr\u003e\nInChiKey:XHBVYDAKJHETMP-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nSupplied in DMSO (10mM).\u003cbr\u003e\nA natural process can cause the product to crystallize out of solution. Should it happen, it is advised to heat the solution to approximately 55°C and let it cool down before use.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847419121833,"sku":"ab146597","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab146597","provider":"Iright","version":"1.0","type":"link"}