{"product_id":"abcam-ab160624","title":"Abcam, ab160624, Recombinant Human FAM131B protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human FAM131B protein is a Human Full Length protein, in the 1 to 332 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q86XD5,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nFAM131B also known as Family with Sequence Similarity 131 Member B is a 33 kDa protein. It is expressed in various tissues including the heart liver and skeletal muscles. The protein is intracellular and appears to play a role in cellular processes by interacting with other proteins involved in signaling pathways.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe FAM131B protein contributes to cellular growth and regulation. It can form complexes with other cellular proteins to modulate their activity. This function suggests that FAM131B might have a hand in orchestrating cellular responses to environmental stimuli assisting cells to adapt and respond effectively.\u003cbr\u003e\nPathways\u003cbr\u003e\nFAM131B is involved in protein kinase signaling and gene expression regulation. It interacts with proteins such as RET and ELK1 which are essential for signal transduction and transcription regulation. This participation indicates that FAM131B acts as a mediator in pathways that influence cellular differentiation and development.\u003cbr\u003e\nStudies have shown the involvement of FAM131B in certain types of cancer especially thyroid carcinoma. The protein forms a fusion with RET to create the RET\/PTC rearrangement which leads to tumor development. In fibrolamellar hepatocellular carcinoma it associates with DNAJB1 suggesting a role in tumorigenesis by contributing to abnormal gene regulation.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843959902377,"sku":"ab160624","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab160624","provider":"Iright","version":"1.0","type":"link"}