{"product_id":"abcam-ab162883","title":"Abcam, ab162883, Recombinant Human ELOVL2 protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human ELOVL2 protein is a Human Full Length protein, in the 1 to 296 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q9NXB9,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe protein ELOVL2 also known as Elongation of very long chain fatty acids protein 2 plays an important role in the elongation of long-chain polyunsaturated fatty acids. Its molecular mass is approximately 33 kDa. ELOVL2 is expressed highly in the liver retina and testes indicating its importance in these tissues where long-chain fatty acids are critical.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nELOVL2 functions in the biosynthesis of polyunsaturated fatty acids which are essential components of phospholipids and are involved in various cellular processes. Although ELOVL2 does not form part of a larger protein complex its enzymatic activity significantly impacts membrane fluidity and function. This fatty acid elongation process supports cellular homeostasis and influences signaling pathways.\u003cbr\u003e\nPathways\u003cbr\u003e\nELOVL2 serves a critical role in the fatty acid elongation pathway. Its activity is closely linked with enzymes like fatty acid desaturases which together maintain lipid composition within membranes. The function of ELOVL2 contributes importantly to the metabolism of fatty acids enabling the synthesis of eicosanoids and docosanoids which are vital signaling molecules.\u003cbr\u003e\nELOVL2 has been associated with age-related decline in physiological functions such as vision and metabolic syndromes like diabetes. Research suggests a connection between alterations in its activity with proteins such as FADS2 which participate in fatty acid metabolism can influence these conditions. Understanding the role of ELOVL2 in these diseases may offer potential therapeutic targets to mitigate their progression.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843937489065,"sku":"ab162883","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab162883","provider":"Iright","version":"1.0","type":"link"}