{"product_id":"abcam-ab17269","title":"Abcam, ab17269, Biotin Anti-M13 antibody [E1]","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nMouse Monoclonal M13 antibody - conjugated to Biotin. Suitable for IHC, ELISA, Flow Cyt, WB and reacts with Enterobacteria phage M13 samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Mouse,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:E1,\u003cbr\u003e\nIsotype:IgG3,\u003cbr\u003e\nLight chain type:unknown,\u003cbr\u003e\nConjugation:Biotin,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Enterobacteria phage M13,\u003cbr\u003e\nApplications:ELISA, Flow Cyt, IHC, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nSpecificity:M13 antibody [E1] (ab17269) is specific for gp3 protein.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nM13 antibody [E1] (ab17269) has numerous uses in screening phage display libraries, especially the screening of single chain antibody libraries.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Purification notes-M13 antibody [E1] (ab17269) is purified using 0.2µm sterile filter., Storage buffer-Preservative: 0.08% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe target 'M13' also known as M13 bacteriophage is a filamentous bacteriophage with a mass of approximately 2 MDa. This bacteriophage infects Escherichia coli bacteria and is characterized by a cylindrical shape with helical symmetry. The M13 phage expresses a protein coat made up of thousands of coat proteins including major coat protein g8p and minor proteins like g3p at its ends. These proteins interact with the bacterial surface for infection.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nM13 phage serves as a tool in phage display technology facilitating the identification of peptide-protein interactions. It does not actively participate in cellular processes but can be part of complex interactions in biotechnological applications. In contrast to lytic phages M13 allows for the continued survival of its host leading to its utilization in non-destructive recombinant DNA methodologies.\u003cbr\u003e\nPathways\u003cbr\u003e\nM13 phage does not integrate into traditional metabolic or signaling pathways of the bacterial host. Instead it exploits the host's machinery for its replication and assembly. Not directly related to human biological pathways its use in phage display allows exploring interactions involving proteins such as antibodies or enzymes including the anti M13 HRP.\u003cbr\u003e\nM13 phage does not directly relate to human diseases but it is essential in diagnostics and therapeutic antibody development. Researchers use phage display libraries to identify antibodies against targets involved in cancer and autoimmune diseases. The interaction between M13 and the Fc region of antibodies is exploited aiding in the precise selection of antibody fragments for therapeutic applications.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46855516586153,"sku":"ab17269","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab17269","provider":"Iright","version":"1.0","type":"link"}