{"product_id":"abcam-ab183948","title":"Abcam, ab183948, Anti-Olfactory Marker Protein\/OMP antibody [EPR19157]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal Olfactory Marker Protein\/OMP antibody. Suitable for WB, IHC-P and reacts with Rat, Mouse samples. Cited in 2 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR19157,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat,\u003cbr\u003e\nApplications:WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nOlfactory Marker Protein (OMP) sometimes referred to as OMP protein or marker protein plays a significant role in the olfactory system. With a molecular mass of approximately 19 kDa OMP is primarily expressed in mature olfactory sensory neurons within the olfactory epithelium. These neurons play an important role in detecting and transmitting odorant signals to the brain. The expression of OMP is often used as an indicator of functional olfactory neurons.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nOMP participates in enhancing the signal transduction process of olfactory sensory neurons. It acts as a modulator in the cascade that follows the initial odorant detection ensuring the proper response and adaptation of the neurons to smells. OMP is not part of any major protein complex but it influences the activity of other signaling molecules within the neuron affecting how signals are shaped and perceived.\u003cbr\u003e\nPathways\u003cbr\u003e\nStudies show that OMP is involved in the olfactory signal transduction pathway. This pathway includes interactions with other proteins like cyclic nucleotide-gated channels which are critical for converting chemical signals from odorants into electrical signals in neurons. By modulating these pathways OMP contributes to the accurate representation of olfactory information ultimately affecting the brain's sensory perception.\u003cbr\u003e\nChanges in OMP expression can relate to conditions impacting the sense of smell such as anosmia which is the loss of olfactory function. Connections exist between OMP and other proteins involved in neurodegenerative diseases like Alzheimer's where olfactory dysfunction is an early symptom. Although not the sole factor OMP's presence in these conditions offers a biomarker potential for early diagnosis or understanding progression.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844190752937,"sku":"ab183948","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab183948","provider":"Iright","version":"1.0","type":"link"}