{"product_id":"abcam-ab189282","title":"Abcam, ab189282, Anti-GPR171 antibody","description":"\u003cp\u003eSize: 50µL\u003cbr\u003e\nRabbit Polyclonal GPR171 antibody. Suitable for IHC-P, WB, ICC\/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human GPR171 aa 100-200.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:IHC-P, ICC\/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human GPR171 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.O14626\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nGPR171 also known as Probable G-protein coupled receptor 171 is a type of receptor involved in signal transduction. With a mass of approximately 40kDa GPR171 is part of the GPCR family. It is expressed in various tissues including the brain and immune cells. This receptor functions by interacting with ligands and activating intracellular signaling cascades which are integral to the receptor’s mechanical role in physiological processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nGPR171 affects neurotransmission and immune response regulation. It interacts with other proteins to form complexes that modulate cellular communication. Its expression within the brain indicates a potential role in neurological functions while in immune cells GPR171 participates in modulating immune responses. The wide expression pattern suggests that it may have multiple roles across different cell types.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe GPR171 mechanism is associated with neuropeptide signaling and inflammatory response pathways. It interacts with other GPCRs and intracellular signaling proteins which are essential for transmitting signals that trigger these pathways. GPR171 may also relate to proteins like opioid receptors involved in modifying pain perception and pleasure sensations highlighting its potential influence on the nervous system.\u003cbr\u003e\nGPR171 has connections to neurological and inflammatory conditions. Its role in brain signaling pathways links it to potential implications in disorders such as anxiety where it may interact with other GPCR proteins. In inflammatory disorders GPR171 may influence immune cell activity possibly relating to proteins like cytokine receptors known to mediate immune responses. Understanding these connections helps to provide insight into therapeutic targeting of GPR171 in these conditions.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854222119081,"sku":"ab189282","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab189282","provider":"Iright","version":"1.0","type":"link"}