{"product_id":"abcam-ab213161","title":"Abcam, ab213161, Anti-ARMC3 antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal ARMC3 antibody. Suitable for ICC\/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ARMC3 aa 750-850 conjugated to Keyhole Limpet Haemocyanin.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human ARMC3 aa 750-850 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.Q5W041\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4Preservative: 0.02% Proclin 300Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nARMC3 also known as Armadillo Repeat Containing 3 acts as a structural protein involved in intracellular processes. This protein weighs approximately 78 kDa and is highly conserved across different species. Expression of ARMC3 is mainly noted in tissues such as the testis and brain indicating its involvement in specific cellular functions within these organs.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nARMC3 plays a role in cellular structure and signaling. Research indicates that ARMC3 participates in forming protein complexes that assist in signal transduction and cytoskeletal arrangements. These complexes are essential for maintaining cellular integrity and function highlighting the protein's importance in regulating cellular behavior and communication.\u003cbr\u003e\nPathways\u003cbr\u003e\nARMC3 interacts with other proteins in cytoskeletal organization and cell signaling pathways. It is known to engage in interactions with other structural proteins such as β-catenin which is critical in the Wnt signaling pathway. This engagement suggests its role in facilitating communication between cellular components and impacting cellular responses through modulation of pathway activities.\u003cbr\u003e\nARMC3 shows associations with ciliopathies and neurodegenerative diseases. Disruptions in ARMC3 expression or function can lead to developmental disorders affecting cilia structure and function. Additionally ARMC3 interactions with proteins like LRRK2 suggest potential links to Parkinson’s disease where cytoskeletal dynamics play an important role in disease pathology. Understanding the exact contribution of ARMC3 in these contexts remains a significant area of research.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854239453353,"sku":"ab213161","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab213161","provider":"Iright","version":"1.0","type":"link"}