{"product_id":"abcam-ab213695","title":"Abcam, ab213695, Anti-Ninjurin 1 antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal Ninjurin 1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human NINJ1 aa 1-100 conjugated to Keyhole Limpet Haemocyanin.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human NINJ1 aa 1-100 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.Q92982\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4Preservative: 0.02% Proclin 300Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nNinjurin 1 also known as ‘NINJ1’ 'ninjurin' or 'ninjurin-1' is a vital protein with a molecular mass of about 16 kDa. This protein is expressed in several tissues such as the neural lineage including Schwann cells and dorsal root ganglion neurons. Ninjurin 1 plays a mechanical role in cell adhesion and communication. Detailed studies reveal that Ninjurin 1 directly participates in the formation of cell-cell junctions indicating an important role in tissue integrity and repair.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nNinjurin 1 is implicated in neural development and immune response. It is not part of a larger protein complex but it interacts with cell membranes promoting cell migration and regeneration. This makes it essential in processes like nerve injury repair and the maintenance of peripheral nerve structure. As a mediator Ninjurin 1 helps in the coordination between cellular responses and environmental signals influencing how cells react to damage and inflammation.\u003cbr\u003e\nPathways\u003cbr\u003e\nNinjurin 1 is an important component in nerve regeneration and immune response pathways. It supports the axonal outgrowth and Schwann cell migration essential after nerve damage. Additionally it’s related to molecules involved in inflammatory signaling pathways like cytokines and toll-like receptors. These interactions facilitate Ninjurin 1’s involvement in orchestrating cellular events that lead to wound healing and immune cell trafficking.\u003cbr\u003e\nNinjurin 1 shows relevance to neurodegenerative diseases and autoimmune conditions. It supports nerve regeneration making it a focus in neuropathic pain management and multiple sclerosis research. Connection with proteins such as nerve growth factor (NGF) and interleukins further elucidates its disease-related interactions. Research continues to explore how modulating Ninjurin 1 expression can provide therapeutic benefits in these contexts.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854365642921,"sku":"ab213695","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab213695","provider":"Iright","version":"1.0","type":"link"}