{"product_id":"abcam-ab218296","title":"Abcam, ab218296, SMIFH2 Formin FH2 Domain Inhibitor","description":"\u003cp\u003eSize: 10mg \/ 25mg \/ 50mg\u003cbr\u003e\nMW 377.2 Da, Purity \u0026gt;99%. Cell-permeable inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation (IC 50  = ~15 μM) and processive barbed end elongation. Decreases the affinity of formin for the actin filament barbed end. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:340316-62-3,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:377.2 Da,\u003cbr\u003e\nMolecular formula:C15H9BrN2O3S,\u003cbr\u003e\nPubChem:2258538,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:Smifh2,\u003cbr\u003e\nBiological description:Cell-permeable inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation (IC50 = ~15 μM) and processive barbed end elongation. Decreases the affinity of formin for the actin filament barbed end. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.,\u003cbr\u003e\nCanonical smiles:C1=CC(=CC(=C1)Br)N2C(=O)C(=CC3=CC=CO3)C(=O)NC2=S,\u003cbr\u003e\nIsomeric smiles:C1=CC(=CC(=C1)Br)N2C(=O)\/C(=C\/C3=CC=CO3)\/C(=O)NC2=S,\u003cbr\u003e\nInChi:InChI=1S\/C15H9BrN2O3S\/c16-9-3-1-4-10(7-9)18-14(20)12(13(19)17-15(18)22)8-11-5-2-6-21-11\/h1-8H,(H,17,19,22)\/b12-8+,\u003cbr\u003e\nInChiKey:MVFJHEQDISFYIS-XYOKQWHBSA-N,\u003cbr\u003e\nIUPAC Name:(5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847418990761,"sku":"ab218296","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab218296","provider":"Iright","version":"1.0","type":"link"}