{"product_id":"abcam-ab22055","title":"Abcam, ab22055, Anti-SARS Envelope Protein antibody - Coronavirus","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nRabbit Polyclonal VEMP antibody. Suitable for WB and reacts with SARS-CoV samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:SARS-CoV,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nApplications overview\u003cbr\u003e\nTick: Tested and Guaranteed to work X: Will not work —: No data Reviews: Customers have been successful and shared their AbReview\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein G, Storage buffer-pH: 7.4Preservative: 0.05% Sodium azideConstituents: PBS, 0.2% Gelatin, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe SARS Envelope Protein also known as E protein plays an essential role in the mechanical structure and function of the coronavirus. The protein has a mass of approximately 8.4 kDa and is expressed in the envelope of the virus. It functions as a viroporin creating ion channels that are important for the virus's lifecycle. These channels facilitate the transport of ions across the viral membrane contributing to the virus's assembly and budding processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe SARS Envelope Protein exhibits significant functionality in viral pathogenesis and host interaction. It forms part of a larger protein complex in the viral envelope works alongside other structural proteins like the membrane (M) protein and nucleocapsid (N) protein. Through these actions the E protein influences coronavirus virulence assisting in virus-host interactions and the evasion of the host immune response.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe SARS Envelope Protein actively participates in viral replication and assembly pathways. It interacts with host cell machinery to modulate viral and host processes important for replication. It also potentially influences the NF-kB signaling pathway which can affect host inflammation response. Related proteins include the spike (S) protein which helps the virus attach and enter host cells indicating a combined effort in infection spread.\u003cbr\u003e\nThe SARS Envelope Protein has a direct connection to illnesses such as COVID-19 and Severe Acute Respiratory Syndrome (SARS). The protein's role in viral assembly and immune evasion links it to the severity and transmission of these diseases. It is also connected to the IFN path where it can interfere with the host's interferon response a critical aspect of antiviral defense. These interactions make the SARS Envelope Protein a potential target for therapeutic interventions.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850160033961,"sku":"ab22055","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab22055","provider":"Iright","version":"1.0","type":"link"}