{"product_id":"abcam-ab224447","title":"Abcam, ab224447, Anti-RIDA antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal RIDA antibody. Suitable for IHC-P, WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human RIDA aa 50 to C-terminus.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human, Mouse, Rat,\u003cbr\u003e\nApplications:WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human RIDA aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.P52758\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nRIDA also known as Reactive Intermediate Deaminase A functions as an important enzyme in cellular processes. This protein has a molecular weight of approximately 19 kDa and is prominently expressed in various tissues including the liver and kidneys. RIDA acts by deaminating reactive intermediates specifically 2-aminoacrylate which in turn prevents toxic accumulation within cells. Its expression sees influence under various metabolic stress conditions indicating its important role in maintaining cellular homeostasis.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nReactive intermediate deaminase A supports metabolic resilience by engaging in the nitrogen metabolism pathway. It functions as part of a deaminase complex important for processing amino acid intermediates. During this metabolic function RIDA catalyzes the conversion of potentially toxic compounds into less harmful ones facilitating their subsequent expulsion or further processing. Such activity helps maintain the balance of available nitrogenous compounds in the cell which is necessary for proper cellular function.\u003cbr\u003e\nPathways\u003cbr\u003e\nReactive intermediate deaminase A integrates into the amino acid metabolism and the central nitrogen metabolism pathways. These pathways involve several interactive proteins like serine hydroxymethyltransferase supporting the correct regulation and maintenance of cellular nitrogen balance. RIDA collaborates with these proteins to ensure that amino acid degradation is smooth and without the buildup of intermediate byproducts.\u003cbr\u003e\nSome studies associate reactive intermediate deaminase A with metabolic disorders involving amino acid imbalances. Diseases such as hyperoxaluria and nonketotic hyperglycinemia show altered activities of proteins connected to RIDA indicating its potential role in these conditions. The connection between RIDA and other proteins like glycine decarboxylase suggests a broader impact on the intricate balance of amino acids in the human body.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854352502953,"sku":"ab224447","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab224447","provider":"Iright","version":"1.0","type":"link"}