{"product_id":"abcam-ab229466","title":"Abcam, ab229466, Anti-LRRFIP1 antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal LRRFIP1 antibody. Suitable for WB, ICC\/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human LRRFIP1.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human LRRFIP1. The exact immunogen used to generate this antibody is proprietary information.Q32MZ4\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.025% Proclin 300Constituents: PBS, 20% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nLRRFIP1 also known as Leucine-Rich Repeat Flightless-Interacting Protein 1 is an important protein involved in several cellular processes. It has an approximate molecular mass of 85 kDa and is expressed in various tissues including immune cells and certain tumor tissues. The protein consists of leucine-rich repeats that play a significant role in its function serving regions that form protein-protein interactions.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nLRRFIP1 participates in innate immune responses and acts as a transcriptional regulator. It is often found as part of a larger protein complex that influences key inflammatory pathways affecting the expression of genes linked to immune response. This protein can modulate signaling pathways influencing cell proliferation and differentiation linking it to the regulation of inflammation and immunity.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe function of LRRFIP1 places it within the NF-kB signaling pathway and Wnt signaling pathway. In the NF-kB pathway LRRFIP1 acts by interacting with proteins that modulate gene transcription related to inflammatory responses. In the Wnt signaling pathway it associates with other proteins to regulate processes important for cell survival and development. The relationship with these pathways demonstrates LRRFIP1’s role in maintaining cellular homeostasis and orchestrating immune responses.\u003cbr\u003e\nLRRFIP1 is connected to autoimmune diseases and certain cancers such as breast cancer. Its deregulation can lead to abnormal immune system activity or tumor progression. The protein engages with inflammatory cytokines and regulatory proteins like STAT3 which contributes to its involvement in these disorders. The study of LRRFIP1 will advance understanding in developing targeted therapies for conditions where it plays a critical role.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46848580485289,"sku":"ab229466","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab229466","provider":"Iright","version":"1.0","type":"link"}