{"product_id":"abcam-ab238170","title":"Abcam, ab238170, Anti-IP6K1 (phospho S118 + S121) antibody [EPR19852] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal IP6K1 phospho S118 + S121 antibody. Carrier free. Suitable for IP, Dot, WB and reacts with Human, Synthetic peptide, Transfected cell lysate - Human samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR19852,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, Dot, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab238170 is the carrier-free version of\u003cbr\u003e\nab214816\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe protein inositol hexakisphosphate kinase 1 (IP6K1) also known as IHPK1 plays an important mechanical role in cellular signaling. It catalyzes the conversion of inositol hexakisphosphate (IP6) to diphosphoinositol pentakisphosphate (IP7). IP6K1 has a molecular mass of approximately 48 kDa. It is expressed in various tissues including the brain testis and pancreas where it is involved in multiple cellular processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nIP6K1 influences several critical cell functions such as energy metabolism cell migration and apoptosis. It also participates in the regulation of insulin secretion. IP6K1 does not primarily form part of a complex; however it interacts with proteins that impact these biological functions. Its role in metabolism and signaling pathways marks it as a significant contributor to maintaining cellular homeostasis.\u003cbr\u003e\nPathways\u003cbr\u003e\nIP6K1 plays a part in the inositol phosphate metabolism and insulin signaling pathways. Within these pathways IP6K1 interacts closely with proteins such as Akt mTOR and other kinases modulating their activities. These interactions affect cellular energy status and influence growth factor signaling pathways impacting numerous downstream biological processes.\u003cbr\u003e\nIP6K1's activity links it to conditions such as type 2 diabetes and obesity. In type 2 diabetes IP6K1 interacts with insulin-signaling proteins affecting glucose homeostasis and insulin sensitivity. The protein's role in obesity relates to its influence on energy metabolism as it can impact energy expenditure and fat storage with potential interactions involving with proteins like leptin and AMPK.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851928359081,"sku":"ab238170","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab238170","provider":"Iright","version":"1.0","type":"link"}