{"product_id":"abcam-ab245214","title":"Abcam, ab245214, Anti-CEBP Delta\/CEBPD antibody [EPR23518-259]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nAnti-CEBP Delta\/CEBPD antibody [EPR23518-259] (ab245214) is a rabbit monoclonal antibody detecting CEBP Delta\/CEBPD in  Western Blot, IP, IHC-P, IHC-Fr . Suitable for  Human, Mouse, Rat . - Biophysical QC for unrivalled batch-batch consistency\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR23518-259,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:IHC-P, IP, WB, IHC-FrSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nWhat is this antibody validated in?\u003cbr\u003e\nAnti-CEBP Delta\/CEBPD antibody [EPR23518-259] (ab245214) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr) in Human, Mouse, Rat samples.\u003cbr\u003e\nWhat is the molecular weight of CEBP Delta\/CEBPD?\u003cbr\u003e\nAnti-CEBP Delta\/CEBPD [EPR23518-259] (ab245214) specifically detects a band for CEBP Delta\/CEBPD (UniProt: Q00322) at a molecular weight of 29kDa.\u003cbr\u003e\nTrial sizes available!\u003cbr\u003e\nTest your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl.\u003cbr\u003e\nDiscover our selection of trial-size antibodies\u003cbr\u003e\nOther related products\u003cbr\u003e\nWe have a range of other formats of antibody clone [EPR23518-259] also available for your convenience: ab245214, Carrier free -\u003cbr\u003e\nab270410\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nCEBP Delta also known as CEBPD is a transcription factor belonging to the CCAAT\/enhancer-binding protein family. This protein has a molecular mass of approximately 28 kDa. It is expressed in various tissues including liver adipose tissue and the immune system reflecting its involvement in distinct physiological processes. CEBPD contains a basic leucine zipper domain allowing it to bind to specific DNA sequences. It acts as a regulator of gene expression by influencing transcriptional activity thereby playing a significant role in controlling cellular differentiation and metabolic processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nCEBP Delta participates in multiple cellular functions including cell cycle regulation and immune response. It modulates proliferation differentiation and apoptosis being important for normal and stress-induced cellular functions. CEBPD forms homodimers or heterodimers with other members of the CEBP family enhancing its functional diversity. This dimerization allows CEBPD to adapt its regulatory role depending on the specific cellular environment and stimuli contributing to metabolic homeostasis and immune functions.\u003cbr\u003e\nPathways\u003cbr\u003e\nCEBP Delta plays a role in pathways related to inflammatory responses and metabolic regulation. It is involved in the NF-κB pathway which is critical for the immune system's response to infection and inflammation working alongside proteins like RELA and NFKB1. Additionally it affects metabolic pathways by regulating genes responsible for lipid and glucose metabolism an action interconnected with other transcription factors like PPARs. Through these pathways CEBPD influences cellular responses to stress and energy requirements.\u003cbr\u003e\nCEBP Delta has been implicated in cancer development and inflammatory diseases. Its dysregulation can contribute to tumorigenesis as CEBPD affects cell proliferation and apoptosis processes often disrupted in cancer. Research suggests a connection between CEBPD and the tumor-suppressing protein p53 indicating a possible regulatory relationship significant in cancer pathways. Furthermore abnormal expression of CEBPD associates with inflammatory disorders such as rheumatoid arthritis where it intersects with cytokines impacting the inflammatory response and joint degradation.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850249064617,"sku":"ab245214","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab245214","provider":"Iright","version":"1.0","type":"link"}