{"product_id":"abcam-ab248237","title":"Abcam, ab248237, Anti-RGS6 antibody [EPR6342] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal RGS6 antibody. Carrier free. Suitable for WB and reacts with Human, Rat, Mouse samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR6342,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab248237 is the carrier-free version of\u003cbr\u003e\nab128943\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nRegulators of G-protein Signaling 6 (RGS6) is a multifunctional protein involved in the negative regulation of G-protein-coupled receptor signaling pathways. Commonly known as RGS6 this protein exhibits a mass of approximately 52 kDa. It is widely expressed in many tissues including the brain heart and liver. RGS6 contains a common RGS domain that accelerates the GTPase activity of G-alpha subunits facilitating the return of these subunits to their inactive GDP-bound form.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nRGS6 contributes to the fine-tuning of cellular signaling processes. It plays a significant role in nervous system function by modulating neurotransmitter release and signal transduction. RGS6 is part of a signaling complex that includes G-protein beta and gamma subunits which further refines its regulatory activity. This complex interaction helps to ensure precise control over timing and intensity of signal propagation in cells.\u003cbr\u003e\nPathways\u003cbr\u003e\nRGS6 is an important component of the G-protein signaling pathway interacting with G-alpha subunits. It also has involvement in the MAPK\/ERK signaling pathway where it influences cellular responses such as proliferation and differentiation. Related proteins in these pathways include other RGS family members and various MAP kinases that collaborate to maintain cellular homeostasis and response to environmental stimuli.\u003cbr\u003e\nRGS6 has implications in conditions such as depression and cancer. It modulates pathways linked to these disorders for instance mood regulation and tumor proliferation. Through these functions RGS6 interacts with proteins like G-protein-coupled receptors and specific transcription factors associated with these diseases offering potential therapeutic targets for treatment.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46852282253481,"sku":"ab248237","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab248237","provider":"Iright","version":"1.0","type":"link"}