{"product_id":"abcam-ab250532","title":"Abcam, ab250532, Anti-TRAX antibody [EPR13929(B)] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal TRAX antibody. Carrier free. Suitable for IP, WB, ICC\/IF and reacts with Mouse, Rat, Human samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR13929(B),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:IP, ICC\/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab250532 is the carrier-free version of\u003cbr\u003e\nab181862\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe protein TRAX also known as Translin-associated factor X functions mechanically as an RNA-binding protein. It plays a role in binding to specific RNA sequences and is involved in RNA transport and stability. The protein has an approximate molecular weight of 31 kDa. TRAX is expressed in various tissues including brain testis and hematopoietic tissues indicating its involvement in diverse biological processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nTRAX interacts with Translin to form a heteromeric complex that is involved in mRNA regulation. The complex participates in the regulation of neural development and synaptic plasticity by stabilizing mRNA and modulating its translation. TRAX’s involvement in RNA processing suggests it may have implications in cellular growth and response to stress.\u003cbr\u003e\nPathways\u003cbr\u003e\nTRAX participates in the RNA regulatory network including the MAPK signaling pathway. It influences stress responses and cell survival by associating with proteins like Translin. This pathway coordination ensures cells can adapt to environmental changes efficiently important in maintaining neuronal health.\u003cbr\u003e\nTRAX has links to neurodegenerative diseases and certain cancers. Alterations in TRAX expression or function can contribute to conditions such as schizophrenia. Its interaction with proteins in disease contexts including Translin suggests that misregulation of the TRAX-Translin complex may play a role in the pathology by impairing RNA transport and stability disrupting cellular functions.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851832938665,"sku":"ab250532","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab250532","provider":"Iright","version":"1.0","type":"link"}