{"product_id":"abcam-ab269696","title":"Abcam, ab269696, Olcegepant, CGRP antagonist","description":"\u003cp\u003eSize: 5mg \/ 10mg \/ 50mg\u003cbr\u003e\nMW 869.6 Da. Potent (IC 50  = 0.03 nM (human) and 6.4 nM (rat)) and selective CGRP-1 receptor antagonist. No significant activity observed against a panel of 75 other receptors. Potently inhibits neurogenic vasodilation.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:204697-65-4,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:869.6 Da,\u003cbr\u003e\nMolecular formula:C38H47Br2N9O5,\u003cbr\u003e\nPubChem:6918509,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble to 50 mM in DMSO,\u003cbr\u003e\nBiochemical name:Olcegepant,\u003cbr\u003e\nBiological description:Potent (IC50 = 0.03 nM (human) and 6.4 nM (rat)) and selective CGRP-1 receptor antagonist. No significant activity observed against a panel of 75 other receptors. Potently inhibits neurogenic vasodilation.,\u003cbr\u003e\nCanonical smiles:C1CN(CCC1N2CC3=CC=CC=C3NC2=O)C(=O)NC(CC4=CC(=C(C(=C4)Br)O)Br)C(=O)NC(CCCCN)C(=O)N5CCN(CC5)C6=CC=NC=C6,\u003cbr\u003e\nIsomeric smiles:C1CN(CCC1N2CC3=CC=CC=C3NC2=O)C(=O)N[C@H](CC4=CC(=C(C(=C4)Br)O)Br)C(=O)N[C@@H](CCCCN)C(=O)N5CCN(CC5)C6=CC=NC=C6,\u003cbr\u003e\nInChi:InChI=1S\/C38H47Br2N9O5\/c39-29-21-25(22-30(40)34(29)50)23-33(45-37(53)48-15-10-28(11-16-48)49-24-26-5-1-2-6-31(26)44-38(49)54)35(51)43-32(7-3-4-12-41)36(52)47-19-17-46(18-20-47)27-8-13-42-14-9-27\/h1-2,5-6,8-9,13-14,21-22,28,32-33,50H,3-4,7,10-12,15-20,23-24,41H2,(H,43,51)(H,44,54)(H,45,53)\/t32-,33+\/m0\/s1,\u003cbr\u003e\nInChiKey:ITIXDWVDFFXNEG-JHOUSYSJSA-N,\u003cbr\u003e\nIUPAC Name:N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847485706409,"sku":"ab269696","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab269696","provider":"Iright","version":"1.0","type":"link"}