{"product_id":"abcam-ab272896","title":"Abcam, ab272896, Anti-CPT1B antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal CPT1B antibody. Suitable for WB, ICC\/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human CPT1B.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:ICC\/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human CPT1B. The exact immunogen used to generate this antibody is proprietary information.Q92523\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.01% Thimerosal (merthiolate)Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nCarnitine palmitoyltransferase 1B (CPT1B) also known as CPT1-M is an enzyme important for fatty acid metabolism. This protein has a molecular weight of about 88 kDa. It is expressed mainly in skeletal muscle tissue and heart. CPT1B is involved in the transport of long-chain fatty acids into the mitochondria which is necessary for beta-oxidation an important metabolic process where fatty acids are broken down to generate energy.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nCPT1B serves an important role in energy metabolism by enabling the conversion of fatty acids into energy within muscle cells. This protein functions as part of the carnitine shuttle complex in conjunction with carnitine-acylcarnitine translocase (CACT) and carnitine palmitoyltransferase 2 (CPT2). This system collectively facilitates the translocation of fatty acids into the mitochondria for subsequent breakdown and energy production.\u003cbr\u003e\nPathways\u003cbr\u003e\nCPT1B plays a role in fatty acid oxidation and energy metabolism pathways. It helps regulate the balance of energy production by modulating the entry of fatty acids into mitochondria. In these pathways CPT1B interacts with CPT2 and CACT ensuring efficient fatty acid transport and oxidation. Through these interactions it helps maintain energy homeostasis especially in tissues with high metabolic demands like muscle and heart.\u003cbr\u003e\nCPT1B has associations with metabolic conditions such as obesity and insulin resistance. When CPT1B function is impaired it can lead to inefficient fatty acid metabolism contributing to lipid accumulation and metabolic dysfunction. Also connections exist between CPT1B activity and symptoms of metabolic syndrome where alterations in CPT1B expression may impact energy utilization and fat storage in muscle tissue.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854229721257,"sku":"ab272896","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab272896","provider":"Iright","version":"1.0","type":"link"}