{"product_id":"abcam-ab277612","title":"Abcam, ab277612, ioSkeletal Myocytes - Human iPSC derived cells","description":"\u003cp\u003eSize: 1Small \/ 1Large\u003cbr\u003e\nioSkeletal Myocytes - Human iPSC derived cells available to order. Introducing the ioSkeletal Myocytes, generated from human induced pluripotent stem cells (iPSCs) using opti-ox, a precise cellular reprogramming technology.\u003cbr\u003e\nKey facts\u003cbr\u003e\nSpecies or organism:Human,\u003cbr\u003e\nForm:LiquidSee storage information\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nIntroducing the ioSkeletal Myocytes, generated from human induced pluripotent stem cells (iPSCs) using opti-ox, a precise cellular reprogramming technology. Human stem cells, within days, convert into consistent and reliable skeletal myocytes, providing a high-quality human model for research, disease modelling and HTS.\u003cbr\u003e\nioSkeletal Myocytes demonstrate robust expression of key proteins of myofilaments (Desmin, Titin, Troponin, Myosin Heavy Chain, Dystrophin), coupled with the transition from immature (MYH3 and MYH8) to mature myosin heavy chain isoforms (MYH1) in a time dependent manner. By Day 10 post revival, skeletal myocytes form striated multinucleated myocytes that contract in response to acetylcholine.\u003cbr\u003e\nHuman skeletal myocytes are available at scale, easy to culture and ready for experiments within days, providing a reliable model for the study of muscle, neuromuscular and associated metabolic disorders.\u003cbr\u003e\nIn partnership with bit.bio\u003cbr\u003e\nKaryotype:\u003cbr\u003e\nNormal\u003cbr\u003e\nSeeding Density:\u003cbr\u003e\n100,000 cells\/cm\u003cbr\u003e\nSeeding compatibility:\u003cbr\u003e\n6-, 12-, 24- and 96-well compatible\u003cbr\u003e\nQuality control:\u003cbr\u003e\nSterility, ICC and gene expression analysis\u003cbr\u003e\nResearch applications:\u003cbr\u003e\nMuscle research, Neuromuscular junction Research, Metabolic research, Drug development, Genetic screening (e.g. CRISPR screening), Contractions assays\u003cbr\u003e\nThis product is subject to limited use licenses from iPS Academia Japan Inc, TET Systems GmbH, ERS Genomics Limited and Sigma-Aldrich Co. LLC and is developed with Bit Bio patented technology. For full details of the licenses and patents please refer to our\u003cbr\u003e\nlimited use license and patent pages\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--196°C, Appropriate long-term storage conditions--196°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46845055008937,"sku":"ab277612","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab277612","provider":"Iright","version":"1.0","type":"link"}